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Università: Politecnico di Milano
Corso di laurea: Biomedical Engineering
Materia: Biomachines
Classificazione: Esame · Altro
Contenuto: Testo d’esame
Formato originale: PDF
Testo: Testo ricercabile

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Materiale universitario di Biomachines per il corso di Biomedical Engineering presso Politecnico di Milano. Il documento tratta: Politecnico di Milano Course of Biomachines (with Laboratory) Surname______________ Name______________ ID nr._________ Mark: __/30 Exercise 1 (7 points) Describe what determines the outlet pressure of either a volumetric or a centrifugal pump during extracorporeal circulation…

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Pagina 1

Politecnico di Milano Course of Biomachines (with Laboratory) Surname______________ Name______________ ID nr._________ Mark: __/30 Exercise 1 (7 points) Describe what determines the outlet pressure of either a volumetric or a centrifugal pump during extracorporeal circulation procedures. Exercise 2 (8 points) Determine the length of the tube to allow a blood transfusion with a flow rate of 300 ml/min (Fig. 1). The fluid pressure at the inlets of tube, that is required to guarantee the desired flow rate, it is equal to 500 mmHg. The venous pressure is 3 mmHg. The circuit is made by a blood bag, a tube having internal diameter of 1/16” and a dialysis needle having internal diameter Di = 1.2 mm and length L = 40 mm. Disregard the pressure drops due to the sharp variations at the junction between the blood bag and the tube and between the tube and the needle. Consider blood viscosity µ = 3 cP and density ρ = 1060 kg/m3. Calculate if the potentially most haemolytic part of the circuit Fig. 1 Blood transfusion induces haemolysis. Exercise 3 (5 points) 1 l/min blood flow rate at a temperature of 19°C, unknown haematocrit and with specific oxygen content of 14 mlO2/dlb, is mixed with 2 l/min arterial blood flow rate with physiological O2 content. Determine the value of the unknown haematocrit to have pO2 = 35 mmHg in the blood mixture. Exercise 4 (10 points) Determine and comment on the blood conditions at the outlet of two different oxygenation circuits assembled by using identical membrane blood oxygenators characterised by the same specific oxygen

Pagina 2

transfer curve and supplied with pure oxygen flow rate at the gas side. 6 5 𝑣 02 [ml02/dlb] 4 3 2 1 0 0 1 2 3 4 5 6 Qb [l/min] Both circuits are supplied with a blood flow rate Qb = 5 l/min in standard venous conditions. Circuit A: the oxygenators are put in parallel, with equal blood flow rate flowing through each one of them. Qb1 OXY 1 Qb pO2=? OXY 2 Qb2 Circuit B: oxygenators OXY 1 and OXY 2 are put in series. Qb pO2=? OXY 1 OXY 2

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