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1 Surname________________ Name________________________ ID (matricola)_____________ Technologies for regenerative medicine - Prof. Manuela T. Raimondi Exam in date 04 September 2019 ------------------------------------------------------------------------------------------------------------------- RULES 1. The exam duration is 60 minutes. 2. The use of a calculator, or any other electronic device, is forbidden. 3. You may not copy and/or converse. 4. Answers will be evaluated only if given in English. 5. Each answer is worth the indicated score, or part of it, if it is partially correct. 6. If the exercise requires mathematical passages, the points are awarded only if all passages are shown inside the spaces provided. 7. The solution of the exam will be published on BeeP. You can view your results following the publication on Beep, according to specific instruction that you will receive. 8. The proposed grade will be published on the Politecnico “servizi on line” portal. Any student wishing to reject the grade should do it through the portal, within the publication period. After this deadline, the grade will be automatically consolidated and verbalised. --------------------------------------------------------------------------------------------------------------- The bioartificial pancreas The intravascular bioartificial pancreas is designed to be connected to an arterial blood vessel in a patient. The device can be modelled as a cylindrical cartridge containing pancreatic β cells, obtained from donors, expanded and embedded in a hydrogel. It is designed to be anastomosed to the patient’s blood vessel through lateral tubes. The insulin synthesised by the β cells diffuses into the circulating blood stream. The blood flux and the cells are separated by a semi-permeable…