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1 Surname____________ Name___________Registration ID (matricola)_____________ Technologies for regenerative medicine - Prof. Manuela T. Raimondi 15 January 2019 - test ------------------------------------------------------------------------------------------------------------------- RULES 1. The exam duration is 60 minutes. 2. The use of a calculator, or any other electronic device, is forbidden. 3. You may not copy and / or converse. 4. Answers will be evaluated only if given in English. 5. Each answer is worth the indicated score, or part of it, if it is partially correct. 6. If the exercise requires mathematical passages, the points are awarded only if all passages are shown, inside the spaces provided. 7. The solution of the exam will be published on BeeP. You can view your results the Monday following the publication on Beep, from 12 (noon) to 13 PM, at Prof. Raimondi’s office, building n. 6 “Giulio Natta”, North tower, second floor. 8. The proposed grade will be published on the Politecnico “servizi on line” portal. Any student wishing to reject the grade should do it through the portal, within the publication period. After this deadline, the grade will be automatically consolidated and verbalised. --------------------------------------------------------------------------------------------------------------- Regenerative therapy for the bladder Consider a therapy for bladder regeneration. The therapeutic strategy consists in muscular cells isolation from a biopsy of the bladder, their expansion in culture, their seeding on a scaffold of polyglycolic acid (PGA), and the orthotopic implant of the cellularized construct. This procedure was used to create tissue-engineered bladders that were implanted in seven patients affected by bladder hypotrophy of neurological…