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- Politecnico di Milano
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- Biomedical Engineering
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- Computational Biology of the Heart
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Laboratorio 1 Open core
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Computational Biology of the HeartOther
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10/03/2021 Exercisecompalethepermeabili}for[KI, [cit), and [Noi)atnotfora humanventricolo cardiomyoeyte. Iam goingtouse theGHKequatore Jr= Pr- Ezer[eri. - [cit. @ 'ÌÌ" RT- c-e'Fer [Pr)±[cmls] f-= 96485CIM ZK= 1 ⾨310← Era { ' Zca= 2 12=8.314JIIMK) Zna=L [D=[VI [tre[Alcuni [Cr)=molar[MIL]= io'Holland) Extracellulareioaicconcentratori: - [città1.8nrillimolar= i.8.10-6l'91cm> [letto= 5.4millimolar= 5.4.iò'Mlcwi [N!),=140millimolar=140.10-6pplcwi Intracellulareionic concentrato»- [Cotti=5.58.10-5millimetri5.58- là" Mk» [K'Ji=148millirnolar= 148.10-6Mam> [Notti= 4.1millimolar= 4.1.10-6111con> transmemkane-P.ttVi-88.324mV N Potentieri. -88.44mV Eri- Effentroci 138mv Ena= 94.31mV CapacitaCn:1µFIcon? Cemento- [KICMAGFJL-Natl-MAGFJ-cah.UA/ntI- - - ÷:÷:* :p::*::c:÷:Ikr 7.3.1 0' ' In.ca;-0.007882t'cadde)- t.72.IO?::d:::::::h::::::::H:c:O:INAK0.016535Inalai -0.007882 Inalassi-0.001897 Netlamenta- : IKEIK,ttkbttkrttksttto- ZINAK= -8.82-io> MIMF Ina:INattnabttnc.lt3.Inak-13Nacaitttnacass)IN 8.78- io-5171µF Ica=Icabtdpcatàcallktàcallnalttcallca) - 2.(Inacaittriacass)Ica= 3.99.1077µF whatisthesituation- àk ÷È¥" sina.mn5.g.'Émm Ica Permeabilità Jr: PrFÈÈi- e'IF we can workoatthepermeabilityPa %ÈvÈv|- @FZRVIRT Saldiateoalues. Ion Permeability[cmls] FÀ1.90.10- '2[noi) \ "a.io" [coi] EIv'ò" II.noi' Afrestathemembraneismachmore permea66to[KIHanto[CI]andEvil Infaetin thiscase themembrane behasvesas ifitis onlypermea66 to[kt] :. VresfI EK= -88.44mV =
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