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Mayer Waves

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Bioengineering of Physiological Control SystemsBy topic

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MAYERWAVES MayerWavesareSonicSLOWOSCILLATIONSoftheRRandSAPVARIABIUTY, thathasbeendiscaricae200yearsago, butwhose SOURCEis stileDISCUSSED RECALL RRVariabilita= howtheRRInterval→ HRChanges over SEVERALBEATS HRIBPM) i go = HR("Z)= Rpr(s) SAPVariability= howtheSYSTOUCARTERIALPRESSOREchangesover SEVERALBEATS RRandSAPUARIABILITY BathRR- VariabilityandSAP- VariabilityareKnowntohave2mainComponentsinFrequency: i 1 . . . . . . - i . . . . . . . i. VERYHIGHCOHERENCE(=1)<㱺 HIGHCORRELATION@LFandHF betwecutue2Variables RESPIRA-110Neffectsall Cardiacvariable,except HFSOURCEofVARIATION(@e 0.25/0.3Hz) R" 1s@""m theSKINRESISTANCE ^yRESPIRATORYSINUSARRHYTMIA' respiratoriPena>=>tes ' ChangosinHR →mTheheartrateissynchronizedwiththeRespiratorynate, tobemorespecific@NORMALCONDITIONS toRESPIRATORY a"""" HRisinphasewithLUNGVOLUME: THRInspirationHRvariabilita= {•apeexpiratiom LFSOURCEofVARIATION(@=0.1Hz) < >MAYERWAVESchamges.in/tRevery=1OH2beatsU-NOTiDENlFlEDCAUSE- SUVARIABILI-14 ANALYZINGtheSTROKEVOLUMESPECTRUMemergesthatwhatevertuecauseofMayerWaves, the SVisnotaffectedma SUhasonlya notabileComponent@HF (duetoRESPIRA-110NACTIVITY) (anyuariability@LF) HYPOTESISon theSOURCES • LFare usuallylinkedtoSYMPATHETICarousal(showadinergicandLongtastingresponse) +IthasbeenObscuredamIncreaseofLFComponentinSTANDING, STRESSandINTENSEBRAINACTIVITY sSonicexpertsareSkepticaboutthishypotesissinceLFcanbealsolinkedtoParasymphateticactivities • H. KOEPCHENputforwandthehighCOMPLEX/TYthatcanhidebehindMayerWaves: POSSIBLESOURCESofLFOSCILLATIONS: 1 1 Oscillatingactivity@SPINALLEVELandinMEDULLA 3 a a VesselsOscillations asanadditionalpompinoMechanismthathelps (uascularizatiom,WEAKERandShowerthoutheHeartPumptought) 3 Oscillations causedbythe BAROREFLEXLOOPCLOSEDtoINSTABILITY ←, - @First,Guyton'sidea✓- " " •…

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